Several studies have shown a significant association between high levels of Gal3 in the blood serum and COVID-19 severity [84,85,86], along with increased pro-inflammatory cytokines (IL-1β, TNF-α, and IL-12), chemokine C-C, and chemokine receptor type 5 (CCR5) expression in T cells [92]. Here, LGALS3 is linked to COVID-19.