NEFL and Alzheimer disease: Moreover, we observed a significant increase in NfL levels in AD and FTD patients compared to CTRL (mean ± SEM; AD, 21.70 ± 1.88 pg/mL vs. CTRL, 12.83 ± 0.87 pg/mL, Generalized Linear Model, padj < 0.001; FTD, 25.28 ± 2.54 pg/mL vs. CTRL, Generalized Linear Model, padj < 0.001).