Furthermore, the specific analysis correlating the presence of these neonatal microglia with the presence of precursors (OPC) and mature oligodendrocytes in CC and cerebellum of the AQP4-KO animals would be of high interest to continue deciphering the molecular bases that bind the AQP4 expression with CNS disorders such as Alzheimer’s, hydrocephalus or NMO, among others. This evidence concerns the gene AQP4 and central nervous system disorder.