IL17A and juvenile idiopathic arthritis: We have shown that carrying IL-17A rs2275913 (AG/AA) or rs8193036 variant genotypes (CT/CC) and IL-10 rs1800896 variant genotypes (TC/CC) increases the risk of JIA, and specifically, the risk of seronegative polyarthritis is increased in the IL-17A rs8193036 variant background.