APOC3 and metabolic dysfunction-associated steatotic liver disease: Xu et al. [44] studied 34 biopsy-proven NAFLD patients and reported that APOC3 SNPs are intimately correlated to serum lipidomics in NAFLD patients, with the SNP rs2070667 being the most lipid-altered, exhibiting downregulatory effect on PUFA-containing TG: TG(54:7), TG(54:8), and TG(56:9) and a predisposition to high-grade lobular inflammation.