ANGPTL3 and steatosis: Fortunately, additional research has examined alterations in the lipoprotein lipidome associated with steatosis and, notwithstanding, genetic conditions that confer protection against steatosis can also impact lipoprotein composition, as demonstrated by Ruhanen et al. [28] through lipidome analysis of lipoproteins of ANGPTL3-LOF human (n = 5) and control subjects (n = 10).