Another partial deletion in TNFAIP3 included exons 7–8 of the gene, which was associated with a de novo case of A20 haploinsufficiency in a child who experienced liver dysfunctions, persistent hepatosplenomegaly, fever with elevated leukocytes, lymphadenopathy, and massive pericardial effusion before her first year of age. Here, TNFAIP3 is linked to pericardial effusion.