Peripheral markers of systemic inflammation still predict a WM microstructure several months after recovery, with more severe inflammation during the acute phase (higher serum C-reactive protein (CRP) levels and leucocyte counts) associating with reduced axial diffusivity at diffusion tensor imaging, suggesting subtle changes in the microtubular structure of axons, which might underpin the neuropsychiatric consequences of COVID-19 [10]. The gene discussed is CRP; the disease is COVID-19.