Primarily, Kaplan–Meier curves of the overall cohort (Figure 1A) and gender-specific cohort (male: Figure 1B, female: Figure 1C) were generated according to the presence or absence of pulmonary hypertension, which was determined using an sPAP cut-off value ≥ 40 mmHg. The gene discussed is PDZK1IP1; the disease is pulmonary arterial hypertension.