The prevalence of HPyVs DNA according to the two histological subtypes of RCC, i.e., CCRCC and PRCC, revealed that HPyVs were less abundant in PRCC tissues (6/15 (40%); 3 HPyV7, 1 HPyV6, and 2 MCPyV) compared to CCRCC ((28/40) (70%) 19 MCPyV, 6 HPyV7, 2 HPyV6, and 1 WUPyV) (Table 2 and Table 3). This evidence concerns the gene PRCC and renal cell carcinoma.