Although IgE-mediated allergy to omega-5 gliadin Tri a 19 typically correlates with WDEIA, wherein physical exercise serves as a cofactor, some patients may present with idiopathic anaphylaxis, exercise-induced symptoms without an evident food connection, food-induced allergic manifestations without exercise, or recurrent acute urticaria [64]. The gene discussed is IGHE; the disease is urticaria.