Results showed that the altered allele of MTHFR rs1801133 (T) carriers have reduced all-cause mortality (HR = 0.69, 95%CI = 0.49–0.98) and breast cancer-specific mortality (HR = 0.58, 95%IC = 0.38–0.89) [71]. The gene discussed is MTHFR; the disease is breast carcinoma.