TNFRSF11A and osteosarcoma: In a study that was conducted recently, it was demonstrated that the interaction between the Receptor Activator of Nuclear Factor Kappa B (RANK) and its ligand (RANKL) had a notable impact on the enhancement of migration, invasion, and metastasis of Osteosarcoma (OS) cells through the facilitation of Epithelial-Mesenchymal Transition (EMT).