The nanocomplexes were tested in vitro in two human neuroblastoma cell lines, and immunofluorescence for MXD3 using Alexa® 488-labelled probes showed a drastic decrease in this factor in treated cells, while the apoptotic rate, evaluated using FITC-labelled annexin V and propidium iodide, increased [86]. This evidence concerns the gene MXD3 and neuroblastoma.