TNF and type 2 diabetes mellitus: In another study on T2DM rats, the daily oral administration of B. animalis 01 (109 CFU) for 15 weeks reduced body weight, food and water intake, FBG, OGTT-AUC, HbA1c, HOMA-IR, TC, LDL-C, LPS, TNF-α, ALT, AST, and MDA while increasing IL-10, CAT, GSH, GSH-Px, and SOD.