APC and malignant colon neoplasm: Janet Alejandra Gutierrez-Uribe et al., 2020 reported that kaempferol-3-O-glycoside isolated from black beans showed downregulated expression of miR-31 and miR-92a along with the KRAS oncogene and increased expression of tumor suppressor genes, APC and AMPK in RKO colon cancer cells [155].