TLR4 and eating disorder: In light of the fact that lipopolysaccharide (LPS) can activate pro-inflammatory pathways, primarily via Toll-like receptor 4 (TLR4), which may induce neuroinflammation in the hypothalamus and downstream homeostatic food intake preferences [22,26], a recent review has proposed insightful connections between the gut microbiome, neuroinflammation, and the pathology of eating disorders, specifically highlighting the role of microglia inflammation in the cause of AN [21].