Recently, Cruceriu et al. [76] reported that C. officinalis could exert anti-cancer activity by inducing apoptosis, activating caspase 3 and caspase 7, and downregulating cyclin D1, D3, A, E, and several cyclin-dependent kinases, suggesting the prospective usage of C. officinalis in cancer management, particularly in cancer prevention, treatment, and palliative care for patients. Here, CASP3 is linked to cancer.