HMOX1 and self-limited childhood occipital epilepsy: Other components from the hydroxycinnamic acid derivatives identified in BOE with proven anti-inflammatory and anti-oxidant effects are para-coumaric acid [29], which acts by decreasing the cell-mediated immune response and the expression of the inflammatory mediators TNF-α and IL-6 and caffeoylquinic acid, which acts by downregulating the NRF2/HO-1 inflammation pathway [30].