In women who intend to become pregnant, women who are pregnant, and women who have given birth within three months, it is essential to monitor A-TPO and A-Tg and thyroid function as well as serum thyroid hormone and TSH levels to identify dysfunction in a timely manner and adjust the treatment strategy to avoid the deleterious effects of hypothyroidism in mother and baby during and after pregnancy. The gene discussed is TG; the disease is thyroiditis.