In contrast, individuals with the presence of aCL in the IgM class showed a higher OR for strokes (1.96-fold; 95% CI: 1.03–3.76; p = 0.032) and DVT (1.79-fold; 95% CI: 1.09–2.95; p = 0.016) within the non-LN group. This evidence concerns the gene ACLY and lobular neoplasia.