In contrast to the discrepancy trend for false-positive results observed in our report, this study demonstrated the sensitivity of the AcuStar® ADAMTS13 activity assay for acute TTP to be 90.1%, with 14/142 (9.8%) patients with undetectable ADAMTS13 activity misdiagnosed. The gene discussed is ADAMTS13; the disease is thrombotic thrombocytopenic purpura.