CMA with adequate resolution to identify the deletion boundary can define whether there is loss of implicated genes contiguous to CYBB in these cases, e.g., XK (Kx blood group antigen), RPGR (retinitis pigmentosa), DMD (Duchenne muscular dystrophy) and OTC (ornithine transcarbamoylase) [187,188]. Here, XK is linked to retinitis pigmentosa.