Our meta-analysis from a total of six studies (n = 2803) showed that the genetic model consisting of CC genotypes of KDR/VEGFR2 (rs2071559) gene polymorphism was associated with a higher risk of gliomas than the model consisting of CT genotypes [OR 1.33 (95% CI 1.11–1.59), p = 0.002, I2 = 0%, random-effects models] (Figure 3C). Here, KDR is linked to central nervous system cancer.