INS and Hyperglycemia: The increase in glycemia that occurred 60 min after the application of dexmedetomidine in the animals in the current research was also observed when this drug was administered at a dose of 10 μg/kg IV in healthy cats due to the activation of alpha-2 receptors located in pancreatic beta cells, which culminates in the inhibition of insulin release and consequent hyperglycemia [44].