At the CAZy-family level (top 30), compared to Hu sheep, CAH significantly increased GH13, GH3, GH28, GH1, GT1, GH92, and GH38 but decreased GT2, GH23, GH43, GH2, GH35, GT0, and GH73 (p < 0.05) (Figure 2D). Here, H3-4 is linked to congenital adrenal hyperplasia.