In addition, this genomic region was previously identified as a QTL associated with resistance to viral load in Holstein cattle [58] and includes genes that have shown differential expression between susceptible and resistant hosts to the mite (KIF3A) [59], mangal-infected and uninfected animals (IL4, IL5, and IL13) [60], and healthy and mastitis-affected cows (IL4) [61]. Here, IL4 is linked to mastitis.