Ramzkhah et al. observed that ASCs obtained from the breast cancer TME produce more IL-4, IL-10, and transforming growth factor beta 1 (TGF-β1), leading to higher levels of CD4+CD25highFOXP3+ T regulatory cells that contribute to the suppression of antitumor immunity [20]. This evidence concerns the gene TGFB1 and breast carcinoma.