JAK1 and ovarian cancer: In ovarian cancer cells, IFNγ induces Bcl3, PD-L1 and IL-8 expression by mechanisms involving increased promoter acetylation, JAK1-STAT1 signaling, p65 NFκB signaling and Bcl3, resulting in increased OC cell proliferation and migration [47,48,49,50,51]; these mechanisms are schematically illustrated in Figure 2.