CD274 and ovarian carcinoma: The positive correlation between IL-8 and PD-L1 in OC was also demonstrated by Wang et al., who showed that co-culture of ascites-derived ovarian cancer cells with CD8+ T cells resulted in increased gene and protein levels of IL-8 and PD-L1 in OC cells [203], and by Wu et al., who demonstrated IL-8 and PD-L1 co-expression in ovarian cancer organoids [204].