An important finding is that a combined evaluation of perfusion and diffusion MRI leads to a better prediction of HGG vs. LGG, IDH1/2 wildtype vs. IDH1/2 mutated gliomas, and high-grade oligodendroglial vs. high-grade astrocytic gliomas, even when taking a different number of predictors into account. The gene discussed is IDH1; the disease is central nervous system cancer.