AR and posterior cortical atrophy: To assess the protein levels of HMGA2 and AR in PCa cells, we conducted Western blot analysis across various PCa cell lines, including parental LNCaP originally derived from lymph node metastasis, C4-2B, a bone metastatic subline of LNCaP, and enzalutamide-resistant C4-2B cells (C4-2B MDVR).