In addition, the monocyte-like cells or mature AML cohort had an overexpression of TNF pathway genes (TRAIL/TNFSF10, TNFAIP2), IL-10 pathway genes (STAT1, HMOX1), and regulators of reactive oxygen species (TXNIP) [28]. The gene discussed is TNFSF10; the disease is acute myeloid leukemia.