In order to further investigate the association between ox-LDL/LOX-1 and IVD, we collected CEP tissues from Lumbar vertebral fracture (LVF), Intervertebral Disc Degeneration(IDD), and Hyperlipidemia with intervertebral disc degeneration (HLP (IDD)) patients for analysis. Here, OLR1 is linked to hyperkeratosis lenticularis perstans.