TDRD12 and Infertility: In addition, screening of exome data from three independent cohorts of infertile men identified eight additional patients with homozygous high-impact variants (two LoF and six missense) in GPAT2, PIWIL2, MOV10L1, and TDRD12 (Table 1, Supplementary Data 1), bringing the total number of variant carriers to 39.