Furthermore, specific deletion of Fgf13 in renal tubular endothelial cells improves mitochondrial homeostasis and endothelial barrier integrity in type 2 diabetic nephropathy (T2DN), as the absence of Fgf13 enhances the action of Parkin, promotes mitophagy, and reduces cell apoptosis, indicating its potential value as a therapeutic target for T2DN [192]. Here, FGF13 is linked to type 2 diabetes nephropathy.