BTG3 and Esophageal atresia: In this study, ANA positivity was more common in females than males, and its positivity rate increased gradually with age, consistent with current research findings.[19–21] Compared to the healthy control group with negative ANA serum, ANA-positive patients exhibited higher levels of EBNA-1-IgG, EBV-EA-IgG, EBV-EA-IgA, and EBV-VCA-IgA, showing a similar trend in EBV-DNA detection positivity.