also reported that circACTN4 could sponge miR‐424‐5p to upregulate YAP1, leading to ICC progression.[14] In the current study, circUGP2 was observed in both the nucleus and cytoplasm of ICC cells, and further investigations revealed that ADGRB1 could also be upregulated by circUGP2 through sponging miR‐3191‐5p. This evidence concerns the gene ADGRB1 and intrahepatic cholangiocarcinoma.