BAX and neoplasm: CDKN1A also interacts with proteins involved in cell apoptosis, such as the Bcl‐2 family inhibitor, Bax, which promotes tumor cell apoptosis.[7] Furthermore, studies have shown that p53 transcriptionally inhibits SLC7A11, a key cysteine/glutamate reverse transporter protein, leading to inhibition of cysteine uptake and increased sensitivity of cells to ferroptosis.[8] Although p53 is highly mutated in different tumor types, its functions are often repressed in many tumors with wild‐type (WT) p53, making tumor cells resistant to chemotherapy.