The expression of LGALS9 cell subsets in the three tumors was quite different, with macrophages being the highest in breast cancer and lower in the rest of the cell subsets, and macrophages, epithelial cells, endothelial cells, and monocytes were all expressed more in colorectal cancer, while macrophages were only moderately expressed in lung cancer, and epithelial cells, endothelial cells, cDCs, CD8+ T cells, CD4+ T cells, and pDCs were all expressed higher (Figures 8E, 9E, 10E). Here, CD4 is linked to breast cancer.