TP53 and cancer: In addition, the inactivation of apoptotic pathways (p53 Signaling, PD-L1 cancer immunotherapy pathway, and DNA damage-induced 14-3-3σ signaling) and the activation of pro-inflammatory pathways (Docosahexaenoic Acid (DHA) Signaling, Systemic Lupus Erythematosus in B Cell Signaling Pathway, Dendritic Cell Maturation, and NAD Signaling Pathway) was noted for the PP group (Figure S5B).