In children with dilated cardiomyopathy, a combined model using cut-off values of KIM-1 ≥ 235, IL-18 ≥ 17.5, and (BNP) > 15 pg/mL distinguished patients with mildly depressed LV (55 > LVEF ≥ 45) and those with LVEF < 45%: ROC curve AUC 0.70 The gene discussed is HAVCR1; the disease is dilated cardiomyopathy.