In children with dilated cardiomyopathy, a combined model using cut-off values of KIM-1 ≥ 235, IL-18 ≥ 17.5, and (BNP) > 15 pg/mL resulted in a distinction between patients with mildly depressed LV (55 > LVEF ≥ 45) and those with LVEF < 45%: ROC curve AUC 0.70 This evidence concerns the gene NPPB and dilated cardiomyopathy.