CD8A and neoplasm: Interestingly, OVA-specific CD8+ T cells primed with the S. epidermidis-expressed ovalbumin had a phenotype of effector or effector memory cells, compared to the ones primed with tumor-derived ovalbumin antigens in control mice, which bore predominantly central memory phenotype, thus underlining the prospect superior effects of commensals in antitumor immunity [60].