TGFB1 and asthma: Reduced expression of TGF-β receptors (TGF-β RI and TGF-β RII) was also found in asthmatics, including a reduction in TGF-β RI in patients with severe asthma [57] and a reduction in TGF-β RII in children with asthma (in comparison to healthy children and children with other atopic diseases) [58].