TGFB1 and asthma: The role of TGF-β in the pathogenesis of asthma is also indicated by a study performed on the Chinese population, which linked a single nucleotide polymorphism (SNP) of the TGF-β1 promoter (rs1800469 identical to C509T) with susceptibility to asthma development and revealed a possible association between another SNP (rs2241712) of the TGF-β1 promoter and this susceptibility [59].