Of note, NMN supplementation protected mice from CCl4‐ or BDL‐aggravated DSS colitis based on ameliorated weight loss, increased colon length, reduced histological severity of colitis, and decreased expression of inflammatory cytokines, such as Il1β and Il6 (Figure 2F‐H; Figure S4E‐H, Supporting Information). The gene discussed is IL1B; the disease is colitis.