HCRT and Cognitive impairment: The results showed that icv.HCRT‐1 showed a decreased ratio of new zone and new object exploration time in the Y‐maze and NOR, respectively, compared with the CTR group, while icv.HCRT‐1+lactate significantly reversed (Figure S6, Supporting Information), suggesting that lactate could significantly ameliorate the cognitive impairment induced by hypcretin‐1.