TCF4 peaks that overlap with MYCN peaks at SEs in both cell lines show enrichment for many CRC TFs, among which HAND2, TBX2, and MYCN are at the top of the list of enriched factors, as identified by ChIP Enrichment Analysis (ChEA) [45] (Fig. S5d,e). The gene discussed is TBX2; the disease is colorectal carcinoma.