Further investigations demonstrated that dysregulated TAZ-AS202 upregulated E2F1 expression, which accelerated NSCLC growth and metastasis by transcriptionally activating a myriad of oncogenes including Eph receptor B2 (EPHB2), a key component of EPH-Ephrin pathway (Gobbi et al., 2023). The gene discussed is E2F1; the disease is non-small cell lung carcinoma.