For instance, HEBP1 was associated with decreased risk of other secondary gout (OR, 0.34, 95% CI, 0.18 to 0.61, p = 4.08 × 10−4) and hallux rigidus (OR, 0.88, 95% CI, 0.81 to 0.95, p = 2.16 × 10−3). This evidence concerns the gene HEBP1 and Hallux rigidus.