Studies have been conducted to study the efficacy of inhibitors of VEGF/VEGF receptors (VEGFRs), like gonadotropin hormone-releasing hormone (GnRH) agonists or anti-VEGF/VEGFR agents in various endometrial pathologies including AUB, endometriosis and malignancies [16-20]. This evidence concerns the gene KDR and endometriosis.