A total of 57 KEGG enrichment pathways were identified (Figure 6F), including 6 significant pathways as follows: Endocrine resistance (P=0.009), drug metabolism -cytochrome P450 (P=0.009), pyrimidine metabolism (P=0.035), adrenergic signaling in cardiomyocytes (P=0.048), prolactin signaling pathway (P=0.048), and African trypanosomiasis (P=0.048). This evidence concerns the gene PRL and human African trypanosomiasis.