CLN3 and juvenile neuronal ceroid lipofuscinosis: Exon-skipping SSOs have been explored for targeting other diseases, such as correcting the reading frame in CLN3 Batten’s disease (below), bypassing an inframe CEP290 exon 41 that carries pathogenic mutations for Jobert syndrome (Ramsbottom et al., 2018), and suppressing a cryptic splice site in CFTR cystic fibrosis (Michaels et al., 2020).